Archive for February 2nd, 2007

Dragon in Iowa

Crypto, Dinosaurs in Literature, Uncategorized, Unexplained Artifact | Posted by Chris Parker
Feb 02 2007

Graphic: Jordan Greywolf

by Megan

My fiance Dennis and I live in a small town in Iowa called Burlington. About two years ago, we were driving in my car down a residential street in the wee hours of morning, coming up on 3 a.m. (I can’t remember why we were out that early; I’ve forgotten.)

The long residential road that we were on heads west to the outskirts of our town, opening up to an area were there is a few apartment complexes, retail stores, a shopping mall, and two very large car dealership lots. Past that are cornfields, woods, highways and an army base.テつ

The army base is said to be very haunted. The biggest car lot is called Shottenkirk, and has so many tall, bright lights that you can see the glow from all the way across town. They run these lights all night long.

As we drove closer and closer to this little shopping area, I just happened to look up above the glaring bright Shottenkirk lights and saw something that I will never forget: It was brown in color, with a long body about 10 feet in length. The body was long and snake-like. It had bat-like wings somewhere between at least 15 to 20 feet across. The head was seahorse-like. It had a skinny tail flowing behind it.

I looked at Dennis and said. “Do you SEE that?!” and he said, “Yeah… oh, my god. What IS that?!” I actually stopped my car in the middle of the road (thankfully no one else was on it) and we just stared with our mouths hanging open. It seemed to kind of slither in midair, hovering above those tall lights above the car dealership, and it would occasionally beat its massive bat-like wings that sprouted out of its back.

Dennis then said, “It looks like… one of those Chinese dragons!!”

And it did – it looked just like those mythical, serpent-like, slithery, winged Chinese dragons! It moved just like the ones you see in cartoons and drawings, slithering up and down in the air! We watched until it rose up higher into the sky, away from the illumination of the lights and out of our range of sight. It was incredible. We both swapped notes and separately drew pictures of what we had seen, then compared them – they are nearly identical.

Call me crazy, but I think we saw a dragon! In Iowa!

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Cheap, Safe Drug Kills Most Cancers

Science, Uncategorized | Posted by Chris Parker
Feb 02 2007

NEWSCIENTIST

It sounds almost too good to be true: a cheap and simple drug that kills almost all cancers by switching off their テ「竄ャナ妬mmortalityテ「竄ャツ. The drug, dichloroacetate (DCA), has already been used for years to treat rare metabolic disorders and so is known to be relatively safe.テつ

It also has no patent, meaning it could be manufactured for a fraction of the cost of newly developed drugs.テつ

Evangelos Michelakis of the University of Alberta in Edmonton, Canada, and his colleagues tested DCA on human cells cultured outside the body and found that it killed lung, breast and brain cancer cells, but not healthy cells. Tumours in rats deliberately infected with human cancer also shrank drastically when they were fed DCA-laced water for several weeks.テつ

DCA attacks a unique feature of cancer cells: the fact that they make their energy throughout the main body of the cell, rather than in distinct organelles called mitochondria. This process, called glycolysis, is inefficient and uses up vast amounts of sugar.テつ

Until now it had been assumed that cancer cells used glycolysis because their mitochondria were irreparably damaged. However, Michelakisテ「竄ャ邃「s experiments prove this is not the case, because DCA reawakened the mitochondria in cancer cells. The cells then withered and died (Cancer Cell, DOI: 10.1016/j.ccr.2006.10.020).テつ

Michelakis suggests that the switch to glycolysis as an energy source occurs when cells in the middle of an abnormal but benign lump donテ「竄ャ邃「t get enough oxygen for their mitochondria to work properly (see diagram). In order to survive, they switch off their mitochondria and start producing energy through glycolysis.テつ

Crucially, though, mitochondria do another job in cells: they activate apoptosis, the process by which abnormal cells self-destruct. When cells switch mitochondria off, they become テ「竄ャナ妬mmortalテ「竄ャツ, outliving other cells in the tumour and so becoming dominant. Once reawakened by DCA, mitochondria reactivate apoptosis and order the abnormal cells to die.テつ

テ「竄ャナ典he results are intriguing because they point to a critical role that mitochondria play:テつthey impart a unique trait to cancer cells that can be exploited for cancer therapy,テ「竄ャツ says Dario Altieri, director of the University of Massachusetts Cancer Center in Worcester.テつ

The phenomenon might also explain how secondary cancers form. Glycolysis generates lactic acid, which can break down the collagen matrix holding cells together. This means abnormal cells can be released and float to other parts of the body, where they seed new tumours.テつ

DCA can cause pain, numbness and gait disturbances in some patients, but this may be a price worth paying if it turns out to be effective against all cancers. The next step is to run clinical trials of DCA in people with cancer. These may have to be funded by charities, universities and governments: pharmaceutical companies are unlikely to pay because they canテ「竄ャ邃「t make money on unpatented medicines. The pay-off is that if DCA does work, it will be easy to manufacture and dirt cheap.テつ

Paul Clarke, a cancer cell biologist at the University of Dundee in the UK, says the findings challenge the current assumption that mutations, not metabolism, spark off cancers. テ「竄ャナ典he question is: which comes first?テ「竄ャツ he says.テつ

S8int.com Odds and Ends (On which we’re seeking a little help)

Crypto, Dinosaurs in Literature, s8int.com, Science, Uncategorized, Unexplained Artifact | Posted by Chris Parker
Feb 02 2007

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Here at s8int.com. we’ve got a bit of a time crunch going. Normally, we’d take time to run down more information about these objects before we presented them. Not having the time for that at the moment, we’re publishing them and asking for help.

If you can help with these identifications or can provide some missing information it would be much appreciated…..s8int.com

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